
Made in USA

BioClosure Systems |

BioClosure high purity container closures work with vessels of glass, metal, or plastic. Stoppers, caps, True Unions, GL45’s, and other styles, with or without tubing inserts, are available. READ MORE... |
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Gamma Irradiation Services |

Have your single use system gamma irradiated before it arrives at your location and save the additional inventorying, transportation costs, and transit time.
Bagged and labeled products are picked up from AdvantaPure’s facility and conveyed to a local gamma irradiation service provider. Using Cobalt 60 radiation, microorganisms and bacteria are destroyed while your single use system remains in its original packaging. Products are then returned to AdvantaPure for final inspection and shipment to your location. |
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Single Use Molded Connections
Single use AdvantaFlex manifolds are manufactured by molding straight sections of tubing or hose with connectors of various styles such as T's, Y's, and Tri-Clamps®. Molded connectors provide a seamless transition for a continuous, unrestricted, leak-proof flow by eliminating barbed fittings. AdvantaFlex molded TPE manifolds are custom made to your specifications. Choose from the connection options listed here or suggest your own.
| Y CONNECTOR |
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| Size: |
.375" I.D. x .625" O.D.
(9.53mm I.D. x 15.88mm O.D.) |
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Other sizes in development |
| T CONNECTOR |
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| Size Range: |
.188" I.D. x .438" O.D.
(4.78mm I.D. x 11.13mm O.D.) |
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| to: |
.500" I.D. x .750" O.D.
(12.70mm I.D. x 19.05mm O.D.) |
| CROSS |
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| Size Range: |
.375" I.D. x .625" O.D.
(9.53mm I.D. x 15.88mm O.D.) |
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| to: |
.500" I.D. x .750" O.D.
(12.70mm I.D. x 19.05mm O.D.) |
| REDUCER CONNECTOR |
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| Size Range: |
.250" I.D. to .125" I.D. x .375" O.D. to .250" O.D.
(6.35mm I.D. to 3.18mm I.D. x 9.53mm O.D. to 6.35mm O.D.) |
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.375" I.D. to .125" I.D. x . 625" O.D. to .250" O.D.
(9.53mm I.D. to 3.18mm I.D. x 15.88mm O.D. to 6.35mm O.D.)
Most any OD/ID size combination can be manufactured, depending on tubing size availability. |
| TRI-CLAMP® |
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| Size Range: |
.375" I.D. x .625" O.D.
(9.53mm I.D. x 15.88mm O.D.) |
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| to |
.500" I.D. x .750" O.D.
(12.70mm I.D. x 22.23mm O.D.)
Other sizes in development
Available with polysulfone or stainless steel backing cups. |
| MINI TRI-CLAMP® |
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| Size Range: |
.125" I.D. x .250" O.D.
(3.18mm I.D. x 6.35mm O.D.) |
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.375" I.D. x .625" O.D.
(9.53mm I.D. x 15.88mm O.D.)
Most sizes available with polysulfone or stainless steel backing cups; some larger sizes available with stainless steel only. |
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| APPLICATIONS |
- Sterile filling
- Vaccine production
- Pharmaceutical sampling and delivery systems
- Peristaltic pump transfer
- Single-use systems
- Bioreactor processes
- Cell media, harvesting, and fermentation
- Pharmaceutical production and processing
- High purity water transfer
- Filtration

Because of its ability to be sealed and welded, AdvantaFlex is ideal for filling and sampling applications.
Click Here for Information
on AdvantaFlex Tubing
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| CONNECTION OPTIONS |
OVERMOLDED TRI-CLAMP® ENDS
A new option for sanitary connections is available . . . overmolded sanitary ends for PVC, TPE, and TPR tubing and hose. Injection molded from USP Class VI Hytrel® or polypropylene, overmolded ends feature Tri-Clamp® and mini Tri-Clamp styles.
CLICK HERE for Information
on Overmolded Ends
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| ADVANTAFLEX ADVANTAGES |
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Excellent weldability and sealability allows leak- free, sterile connections for filling and sampling applications. AdvantaFlex is compatible with all portable welding and heat-sealing equipment.
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AdvantaFlex offers excellent life in peristaltic pumps. |
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